Resting-state functional connectivity abnormalities in patients with obsessive-compulsive disorder and their healthy first-degree relatives.

@article{Hou2014RestingstateFC,
  title={Resting-state functional connectivity abnormalities in patients with obsessive-compulsive disorder and their healthy first-degree relatives.},
  author={Jing-ming Hou and Mingming Zhao and Wei Zhang and Ling-heng Song and Wen-jing Wu and Jian Wang and Dai-quan Zhou and Bing Xie and Mei Hua He and Jun-Wei Guo and Wei Qu and Haitao Li},
  journal={Journal of psychiatry & neuroscience : JPN},
  year={2014},
  volume={39 5},
  pages={304-11}
}
BACKGROUND Obsessive-compulsive disorder (OCD) is a common, heritable neuropsychiatric disorder, hypothetically underpinned by dysfunction of brain cortical-striatal-thalamic-cortical (CSTC) circuits; however, the extent of brain functional abnormalities in individuals with OCD is unclear, and the genetic basis of this disorder is poorly understood. We determined the whole brain functional connectivity patterns in patients with OCD and their healthy first-degree relatives. METHODS We used… CONTINUE READING

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