Resting state default‐mode network connectivity in early depression using a seed region‐of‐interest analysis: Decreased connectivity with caudate nucleus

  title={Resting state default‐mode network connectivity in early depression using a seed region‐of‐interest analysis: Decreased connectivity with caudate nucleus},
  author={Robyn Bluhm and Peter C. Williamson and Ruth A. Lanius and Jean Th{\'e}berge and Maria Densmore and Robert Bartha and Richard W. J. Neufeld and Elizabeth A. Osuch},
  journal={Psychiatry and Clinical Neurosciences},
Aim:  Reports on resting brain activity in healthy controls have described a default‐mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting‐state DMN in relatively early depression before years of medication treatment. The objective of the present study was, therefore, to investigate the DMN in patients seeking help from specialized mental health services for the first time for… 

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