Resting B-cells, EBV-infected B-blasts and established lymphoblastoid cell lines differ in their Rb, p53 and EBNA-5 expression patterns.

Abstract

Using immunofluorescence technique we have analysed the Rb, p53, EBNA-2 and EBNA-5 expression pattern in EBV infected human B-cells and established lymphoblastoid cell lines (LCL-s). Resting B-cells showed only a faint Rb and no p53 immunostaining. The expression of both Rb and p53 increased after EBV infection. The change was first detectable 6 h after… (More)

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@article{Szekely1995RestingBE, title={Resting B-cells, EBV-infected B-blasts and established lymphoblastoid cell lines differ in their Rb, p53 and EBNA-5 expression patterns.}, author={Laszlo Szekely and Katja Pokrovskaja and W. Q. Jiang and Galina Selivanova and M L{\"o}wbeer and Nils R. Ringertz and Klas G. Wiman and Gerald Klein}, journal={Oncogene}, year={1995}, volume={10 9}, pages={1869-74} }