Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression

@article{Bocker2002ResponsivenessOI,
  title={Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression},
  author={U. Böcker and Oleksandr Yezerskyy and P. Feick and T. Manigold and A. Panja and U. Kalina and F. Herweck and S. Rossol and M. Singer},
  journal={International Journal of Colorectal Disease},
  year={2002},
  volume={18},
  pages={25-32}
}
Abstract Background and aims. Luminal bacteria have been implicated in the pathogenesis of inflammatory bowel diseases. Exposure of intestinal epithelial cells (IEC) to bacterial components potentially initiates intestinal inflammation by release of chemokines and recruitment of inflammatory cells. We analyzed receptor expression and signaling pathways involved in activation of human primary IEC and carcinoma-derived cell lines by lipopolysaccharide (LPS). Materials and methods. HT-29/p, HT-29… Expand
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