Responsiveness of human neonates to the odor of 5α-androst-16-en-3-one: a behavioral paradox?

  title={Responsiveness of human neonates to the odor of 5α-androst-16-en-3-one: a behavioral paradox?},
  author={Helene M. Loos and S{\'e}bastien Doucet and Robert Soussignan and Constanze Hartmann and Karine Durand and Ralf Dittrich and Paul Antoine Sagot and Andrea Buettner and Benoist Schaal},
  journal={Chemical senses},
  volume={39 8},
The odorous steroid 5α-androst-16-en-3-one (AND) occurs in numerous biological fluids in mammals, including man, where it is believed to play a chemocommunicative role. As AND was recently detected in milk and amniotic fluid, sensitivity and hedonic responses to this substance were assessed in human neonates. To this aim, respiration and facial expressions were recorded in 3-day-old newborns in response to aqueous solutions of AND, ranging from 500ng/mL to 0.5 fg/mL. Although analyses of… CONTINUE READING
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