Responsiveness, effect size, and smallest detectable difference of Magnetic Resonance Imaging in knee osteoarthritis.

@article{Hunter2006ResponsivenessES,
  title={Responsiveness, effect size, and smallest detectable difference of Magnetic Resonance Imaging in knee osteoarthritis.},
  author={David J. Hunter and Philip G. Conaghan and Charles G. Peterfy and D Bloch and Ali Guermazi and Thasia Woodworth and Ralph Stevens and Harry K. Genant},
  journal={Osteoarthritis and cartilage},
  year={2006},
  volume={14 Suppl A},
  pages={
          A112-5
        }
}
OBJECTIVE The aim of this study was to determine the responsiveness, effect size (ES) and smallest detectable difference (SDD) of two Magnetic Resonance Imaging (MRI) measures for osteoarthritis (OA) of the knee: a whole-organ semiquantitative evaluation and cartilage volume. DESIGN This analysis was performed on a dataset from a randomized, double-blind trial (Roche NI-15713) conducted in 1998 of a novel therapy in subjects with mild-moderate knee OA, with MRI at baseline and 6-month follow… CONTINUE READING

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