Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes

@article{Aggeli1997ResponsiveGF,
  title={Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes},
  author={A. Aggeli and M. Bell and N. Boden and J. N. Keen and P. Knowles and T. McLeish and M. Pitkeathly and S. Radford},
  journal={Nature},
  year={1997},
  volume={386},
  pages={259-262}
}
Molecular self-assembly is becoming an increasingly popular route to new supramolecular structures and molecular materials1–7. The inspiration for such structures is commonly derived from self-assembling systems in biology. Here we show that a biological motif, the peptide β-sheet, can be exploited in designed oligopeptides that self-assemble into polymeric tapes and with potentially useful mechanical properties. We describe the construction of oligopeptides, rationally designed or based on… Expand
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