Responses to sulfur dioxide and exercise by medication-dependent asthmatics: effect of varying medication levels.

@article{Linn1990ResponsesTS,
  title={Responses to sulfur dioxide and exercise by medication-dependent asthmatics: effect of varying medication levels.},
  author={William S. Linn and Dr. Adil E. Shamoo and Rhoda Peng and Kenneth W. Clark and Edward L. Avol and Jack D. Hackney},
  journal={Archives of environmental health},
  year={1990},
  volume={45 1},
  pages={24-30}
}
Twenty-one volunteers with moderate to severe asthma were exposed to sulfur dioxide (SO2) at concentrations of 0 (control), 0.3, and 0.6 ppm in each of three medication states: (1) low (much of their usual asthma medication withheld), (2) normal (each subject on his own usual medication schedule), and (3) high (usual medication supplemented by inhaled metaproterenol before exposure). Theophylline, the medication usually taken by subjects, was often supplemented by beta-adrenergics. Exposures… CONTINUE READING