Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model.

@article{Belin2012ResponsesTN,
  title={Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model.},
  author={David Belin and V{\'e}ronique Deroche-Gamonet},
  journal={Cold Spring Harbor perspectives in medicine},
  year={2012},
  volume={2 11}
}
Epidemiological studies have revealed striking associations between several distinct behavioral/personality traits and drug addiction, with a large emphasis on the sensation-seeking trait and the associated impulsive dimension of personality. However, in human studies, it is difficult to identify whether personality/behavioral traits actually contribute to increased vulnerability to drug addiction or reflect psychobiological adaptations to chronic drug exposure. Here we show how animal models… CONTINUE READING