Responses of the Na+/H+ exchanger of European flounder red blood cells to hypertonic, beta-adrenergic and acidotic stimuli.

@article{Weaver1999ResponsesOT,
  title={Responses of the Na+/H+ exchanger of European flounder red blood cells to hypertonic, beta-adrenergic and acidotic stimuli.},
  author={Y. R. Weaver and Katrin Kiessling and Andrew R. Cossins},
  journal={The Journal of experimental biology},
  year={1999},
  volume={202 Pt 1},
  pages={21-32}
}
The transport pathways mediating regulatory volume increase (RVI) and beta-adrenergic responses in red cells of the European flounder Platichthys flesus have been investigated. Hypertonic treatment under a low-PO2 atmosphere led to a complete RVI and to a three- to fourfold increase in Na+ influx. The RVI and the activated Na+ influx were blocked by the transport inhibitors amiloride and 4, 4'-diisothiocyanatostilbene-2,2'-disulphonic acid (DIDS), both at a concentration of 10(-4 )mol l-1, and… CONTINUE READING
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