Responses of striatal neurons in the behaving monkey. 3. Effects of iontophoretically applied dopamine on normal responsiveness.

@article{Rolls1984ResponsesOS,
  title={Responses of striatal neurons in the behaving monkey. 3. Effects of iontophoretically applied dopamine on normal responsiveness.},
  author={Edmund T. Rolls and Simon J. Thorpe and Michael Boytim and Istv{\'a}n Szab{\'o} and David I Perrett},
  journal={Neuroscience},
  year={1984},
  volume={12 4},
  pages={1201-12}
}
In order to analyse the functions of dopamine, the effects of the iontophoretic application of dopamine on the responsiveness of striatal neurons to their normal inputs were investigated in the behaving monkey. It was shown that many neurons in the putamen had responses related to movements, of for example the mouth. Iontophoretically applied dopamine decreased the spontaneous firing rates of 178 of 267 neurons (67%) tested in the putamen, caudate nucleus, and the adjacent prefrontal cortex… CONTINUE READING

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