Responses of small intestinal architecture and function over time to environmental factors in a tropical population.

@article{Kelly2004ResponsesOS,
  title={Responses of small intestinal architecture and function over time to environmental factors in a tropical population.},
  author={Paul Kelly and Ian Menzies and Roger Crane and Isaac S Zulu and Carole Nickols and Roger M. Feakins and James C. L. Mwansa and Victor C. Mudenda and Max Katubulushi and Steve Greenwald and Michael Farthing},
  journal={The American journal of tropical medicine and hygiene},
  year={2004},
  volume={70 4},
  pages={412-9}
}
To determine the response of the small intestinal mucosa to environmental conditions, we studied changes in mucosal architecture and function in a longitudinal cohort study in African adults. Over three consecutive years, 238 adults submitted monthly stool samples for parasitologic and bacteriologic analysis and underwent an annual endoscopic jejunal biopsy for mucosal morphometry. Absorption and permeability assays were performed on the same day as the enteroscopy. Variation in mucosal… CONTINUE READING

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