Responses of oxidative stress biomarkers and DNA damage on a freshwater snail (Bellamya aeruginosa) stressed by ethylbenzene.

@article{Zheng2013ResponsesOO,
  title={Responses of oxidative stress biomarkers and DNA damage on a freshwater snail (Bellamya aeruginosa) stressed by ethylbenzene.},
  author={Shimei Zheng and Yingying Wang and Qixing Zhou and Cuihong Chen},
  journal={Archives of environmental contamination and toxicology},
  year={2013},
  volume={65 2},
  pages={251-9}
}
Ethylbenzene is classified as a priority pollutant; however, toxicity data, especially those regarding sublethal toxicity, are rarely reported on gastropods. The present work was performed to elucidate the sublethal effects of ethylbenzene using a freshwater snail, Bellamya aeruginosa (Reeve), exposed to ethylbenzene for 21 days followed by a 17-day recovery period. Superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), reduced glutathione (GSH), and malonyldialdehyde (MDA… CONTINUE READING

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CATALASEGene product plays role in biological processOxidative Stress
Superoxide dismutase ( SOD ) , catalase ( CAT ) , glutathione S - transferase ( GST ) , reduced glutathione ( GSH ) , and malonyldialdehyde ( MDA ) were used as biomarkers to evaluate oxidative stress in hepatopancreas of snails .
At the end of the recovery period , the repair of DNA damage was not yet completed , showing that DNA repair requires more time .
At the end of the recovery period , the repair of DNA damage was not yet completed , showing that DNA repair requires more time .
Alkaline comet assay showed that ethylbenzene could significantly induce DNA damage in hepatopancreas of snails , and there was a good dose- and time - response in DNA damage , indicating potential genotoxicity of ethylbenzene on snails .
Alkaline comet assay showed that ethylbenzene could significantly induce DNA damage in hepatopancreas of snails , and there was a good dose- and time - response in DNA damage , indicating potential genotoxicity of ethylbenzene on snails .
DNA RepairBiological process results from biological processDNA Damage
At the end of the recovery period , the repair of DNA damage was not yet completed , showing that DNA repair requires more time .
Alkaline comet assay showed that ethylbenzene could significantly induce DNA damage in hepatopancreas of snails , and there was a good dose- and time - response in DNA damage , indicating potential genotoxicity of ethylbenzene on snails .
Alkaline comet assay showed that ethylbenzene could significantly induce DNA damage in hepatopancreas of snails , and there was a good dose- and time - response in DNA damage , indicating potential genotoxicity of ethylbenzene on snails .
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