Response to temporal parameter fluctuations in biochemical networks.

  title={Response to temporal parameter fluctuations in biochemical networks.},
  author={Wolfram Liebermeister},
  journal={Journal of theoretical biology},
  volume={234 3},
Metabolic response coefficients describe how variables in metabolic systems, like steady state concentrations, respond to small changes of kinetic parameters. To extend this concept to temporal parameter fluctuations, we define spectral response coefficients that relate Fourier components of concentrations and fluxes to Fourier components of the underlying parameters. It is also straightforward to generalize other concepts from metabolic control theory, such as control coefficients with their… CONTINUE READING

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