Response to nonsteroidal anti-inflammatory drugs in African Americans with osteoarthritis of the knee.

@article{Essex2012ResponseTN,
  title={Response to nonsteroidal anti-inflammatory drugs in African Americans with osteoarthritis of the knee.},
  author={Margaret Noyes Essex and Maureen O'connell and Pritha Bhadra Brown},
  journal={The Journal of international medical research},
  year={2012},
  volume={40 6},
  pages={
          2251-66
        }
}
OBJECTIVE This 6-week, randomized, double-blind, parallel-group study compared the analgesic efficacy, tolerability and safety of celecoxib, naproxen and placebo in African Americans with osteoarthritis (OA) of the knee. METHODS A total of 322 patients aged ≥ 45 years with OA of the knee in a flare state received 200 mg celecoxib orally once daily, 500 mg naproxen orally twice daily or placebo for 6 weeks. The primary endpoint was change from baseline in the Patient's Assessment of Arthritis… CONTINUE READING

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