Response to conjugate pneumococcal and Haemophilus influenzae type b vaccines in asplenic patients.

@article{MeerveldEggink2011ResponseTC,
  title={Response to conjugate pneumococcal and Haemophilus influenzae type b vaccines in asplenic patients.},
  author={Aafke Meerveld-Eggink and Okke de Weerdt and Heleen van Velzen-Blad and Douwe Hedde Biesma and Ger T. Rijkers},
  journal={Vaccine},
  year={2011},
  volume={29 4},
  pages={675-80}
}
We determined the immunogenicity of conjugated Haemophilus influenzae type b and pneumococcal vaccines by quantitative analysis of the antibody response in asplenic patients. To that end, we vaccinated 92 patients with a conjugated Hib vaccine and 54 received two doses of conjugated pneumococcal vaccine (PCV7), followed at six months by a plain polysaccharide pneumococcal vaccine (PPV23). Antibody concentrations were measured before and three weeks after vaccination. After one dose of… CONTINUE READING
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