Response to caffeine and ryanodine receptor isoforms in mouse skeletal muscles.

  title={Response to caffeine and ryanodine receptor isoforms in mouse skeletal muscles.},
  author={Roberto Rossi and Roberto Bottinelli and Vincenzo Sorrentino and Carlo Reggiani},
  journal={American journal of physiology. Cell physiology},
  volume={281 2},
The response to caffeine was studied in mouse muscles [diaphragm, soleus, and extensor digitorum longus (EDL)] with different ryanodine receptor isoform (RyR1, RyR3) composition and in single permeabilized muscle fibers dissected from diaphragm of wild-type (WT) and RyR3-deficient (RyR3-/-) mice at 1, 15, 30, and 60 postnatal days (PND). The caffeine response decreased during development, and, in adult mice, was greater in diaphragm, lower in EDL, and intermediate in soleus. This suggests a… CONTINUE READING
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Computer program for calculating total from specified free or free from specified total ionic concentrations in C593 CAFFEINE CONTRACTURE AND RYANODINE RECEPTORS AJP-Cell Physiol

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