Response to Rv2628 latency antigen associates with cured tuberculosis and remote infection.

@article{Goletti2010ResponseTR,
  title={Response to Rv2628 latency antigen associates with cured tuberculosis and remote infection.},
  author={Delia Goletti and Ornella Butera and Valentina Vanini and Francesco Nicola Lauria and Christoph Lange and Kees L M C Franken and Claudio Angeletti and Tom H. M. Ottenhoff and Enrico Girardi},
  journal={The European respiratory journal},
  year={2010},
  volume={36 1},
  pages={135-42}
}
Interferon-gamma release assays based on region of difference 1 antigens have improved diagnosis of latent tuberculosis infection (LTBI). However, these tests cannot discriminate between recently acquired infection (higher risk of progression to active tuberculosis) and remote LTBI. The objective of the present study was to evaluate the T-cell interferon-gamma responses to Mycobacterium tuberculosis DosR-regulon-encoded antigens (latency antigens) compared with QuantiFERON TB-Gold In-Tube (QFT… CONTINUE READING