Response to Comment on: Padmavathi et al. (2010) Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity: Probable Underlying Mechanisms. Diabetes;59:98–104

@article{Padmavathi2010ResponseTC,
  title={Response to Comment on: Padmavathi et al. (2010) Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity: Probable Underlying Mechanisms. Diabetes;59:98–104},
  author={Inagadapa J.N. Padmavathi and Venu Lagishetty and Manchala Raghunath},
  journal={Diabetes},
  year={2010},
  volume={59},
  pages={e3 - e3}
}
We thank Vincent and Rasco (1) for showing interest in our work. In this present study (2), diets were prepared as per AIN 93G formulations, which use chromium (Cr) at a level of 1 mg/kg diet as recommended earlier for rodents (3). Despite this, the finding that the control diet had 1.56 mg Cr/kg diet suggests that this could be due to contributions from other dietary ingredients. This is corroborated by our observation that Cr-restricted diet, in which Cr salt was deleted, had 0.51 mg Cr/kg… 
Impact of maternal chromium restriction on glucose tolerance, plasma insulin and oxidative stress in WNIN rat offspring.
TLDR
Maternal dietary CrR induced IR, impaired glucose tolerance in WNIN rat offspring and was associated with increased oxidative stress, which may predispose them to type 2 diabetes in their later life.
Role of calorie restriction on pathophysiological changes in tongue fat and its relation to increased risk factors of obstructive sleep apnea in WNIN/Ob obese rats
TLDR
The calorie restriction in obese rats reduced the fat deposition around the neck and improves the upper airway structures, the morphology of tongue fibre and increased the stiffness of the tongue, thereby reducing the risk of obstructive sleep apnea.

References

SHOWING 1-6 OF 6 REFERENCES
Comment on: Padmavathi et al. (2010) Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity: Probable Underlying Mechanisms. Diabetes;59:98–104
TLDR
It is believed that the “restrictive” diet is not restrictive and the diet lacking the added Cr is notrictive in terms of this element.
Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity
TLDR
Chronic maternal Cr restriction increased body adiposity probably due to increased stress and altered lipid metabolism in WNIN rat offspring, which may predispose them to obesity and associated diseases in later life.
Dietary chromium decreases insulin resistance in rats fed a high-fat, mineral-imbalanced diet.
Chromium improves insulin response to glucose in rats.
Components of the AIN-93 diets as improvements in the AIN-76A diet.
TLDR
The AIN-93 rodent diets were formulated to substitute for the previous version (AIN-76A) and to improve the performance of animals that consume them and are better choices for studies with laboratory rodents.
al . ( 2010 ) Chronic Maternal Dietary Chromium Restriction Modulates Visceral Adiposity : Probable Underlying Mechanisms
  • 2010