Response to: Monoclonal antibodies targeting CD20

  title={Response to: Monoclonal antibodies targeting CD20},
  author={Christiane Neumann and Alfred Lammens and Wolfgang Schaefer and Guy J Georges and Manfred Schwaiger and Ekkehard Moessner and Karl-Peter Hopfner and Pablo Uma{\~n}a and G. Niederfellner},
the standard rituximab regimen of 375 mg/mm2 based solely on a historical comparison of complete response (CR)/uncon-firmed CR rates from non-randomized Phase 1/2 clinical trials in (relapsed/refractory) follicular non-Hodgkin lymphoma (NHL) patients as it is stated in the letter of Goldenberg and colleagues. In line with this, the cited publications by Morschhauser et al. 5 and Negrea et al. 6 do not claim superiority over rituximab. To claim superiority, the authors would have to provide… CONTINUE READING


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