Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats.

@article{Weng2005ResponsePO,
  title={Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats.},
  author={H. -R. Weng and Patrick M Dougherty},
  journal={Neuroscience},
  year={2005},
  volume={132 3},
  pages={823-31}
}
C fiber dorsal root reflexes (DRR) contribute to neurogenic inflammation and possibly also to touch-evoked pain (allodynia) induced by intradermal capsaicin. The responses of C fibers in the sural nerve to graded mechanical stimuli before and following intradermal capsaicin were studied in 39 adult male rats. Two-thirds of 111 fibers were without spontaneous activity, while the remaining fibers averaged 1.41+/-0.25 spontaneous antidromic spikes per second. Among the quiescent C fibers only two… CONTINUE READING