# Response of the Hodgkin-Huxley neuron to a periodic sequence of biphasic pulses

@article{Borkowski2011ResponseOT, title={Response of the Hodgkin-Huxley neuron to a periodic sequence of biphasic pulses}, author={L. S. Borkowski}, journal={arXiv: Biological Physics}, year={2011} }

We study the response of the Hodgkin-Huxley neuron stimulated periodically by biphasic rectangular current pulses. The optimal response for charge-balanced input is obtained for cathodic-first pulses with an inter-phase gap (IPG) approximately equal 5 ms. For short pulses the topology of the global bifurcation diagram in the period-amplitude plane is approximately invariant with respect to the pulse polarity and shape details. If stimuli are delivered at neuron's resonant frequencies the firing…

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