Response of steroid-refractory chronic graft-versus-host disease to extracorporeal photopheresis correlates with the dose of CD3+ lymphocytes harvested during early treatment cycles.

@article{Bertani2016ResponseOS,
  title={Response of steroid-refractory chronic graft-versus-host disease to extracorporeal photopheresis correlates with the dose of CD3+ lymphocytes harvested during early treatment cycles.},
  author={Giambattista Bertani and Luca Santoleri and Ursula Ferri and P. Locatelli F. Marenco and Giovanni Battista d. Grillo and Elisa Zucchetti and Brunella Forno and Giuliana Lando and Barbara Scarpati and Roberto Cairoli and Silvano Rossini and Clara Cesana},
  journal={Transfusion},
  year={2016},
  volume={56 2},
  pages={
          505-10
        }
}
BACKGROUND Extracorporeal photopheresis (ECP) is a recognized second-line treatment for steroid-refractory chronic graft-versus-host disease (cGVHD). Treatment course is usually long, expensive, and demanding for patients, so predictors for response are needed. We carried out a retrospective study on cGVHD patients treated at our institution with the aim to identify a possible correlation between apheretic yields composition and probability of response. STUDY DESIGN Patients treated for at… CONTINUE READING
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