Response of red blood cell folate to intervention: implications for folate recommendations for the prevention of neural tube defects.

@article{McNulty2000ResponseOR,
  title={Response of red blood cell folate to intervention: implications for folate recommendations for the prevention of neural tube defects.},
  author={Helene McNulty and Geraldine J. Cuskelly and Mary Ward},
  journal={The American journal of clinical nutrition},
  year={2000},
  volume={71 5 Suppl},
  pages={1308S-11S}
}
Committees worldwide have set almost identical folate recommendations for the prevention of the first occurrence of neural tube defects (NTDs). We evaluate these recommendations by reviewing the results of intervention studies that examined the response of red blood cell folate to altered folate intake. Three options are suggested to achieve the extra 400 microg folic acid/d being recommended by the official committees: increased intake of folate-rich foods, dietary folic acid supplementation… CONTINUE READING