Response of plasma membrane to applied hydrostatic pressure in chondrocytes and fibroblasts.

@article{Wright1992ResponseOP,
  title={Response of plasma membrane to applied hydrostatic pressure in chondrocytes and fibroblasts.},
  author={Margaret Wright and Robin A Stockwell and George Nuki},
  journal={Connective tissue research},
  year={1992},
  volume={28 1-2},
  pages={49-70}
}
Effects of applied hydrostatic pressure on transmembrane potentials were investigated in sheep articular chondrocytes and human skin fibroblasts in non-confluent monolayer cultures. Resting potentials in chondrocytes (about -12 mv) and in fibroblasts (about -15 mV) were increased and decreased respectively by over 40% after pressure was applied cyclically (0.33 Hz, 120 mm Hg, 20 minutes). Continuous pressure (120 mm Hg, 20 minutes) caused deplorization in both cell types. Low frequency pressure… CONTINUE READING

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