Response of panic disorder to fixed doses of alprazolam or imipramine.

@article{Uhlenhuth1989ResponseOP,
  title={Response of panic disorder to fixed doses of alprazolam or imipramine.},
  author={Eberhard H. Uhlenhuth and William Matuzas and Richard M. Glass and Christine Easton},
  journal={Journal of affective disorders},
  year={1989},
  volume={17 3},
  pages={
          261-70
        }
}
This paper reports the results of a double-blind comparison of fixed daily doses of 6 mg of alprazolam, 2 mg of alprazolam, 225 mg of imipramine, and placebo for 8 weeks in 81 patients who met DSM-III criteria for panic disorder with or without agoraphobia. Final scores on eight clinical measures were analyzed from all patients who entered the study and from the subset who completed at least 4 weeks of treatment. Eighty-six percent of the high-dose alprazolam patients completed the study. Only… CONTINUE READING

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