Response of murine gamma delta T cells to the synthetic polypeptide poly-Glu50Tyr50.

@article{Cady2000ResponseOM,
  title={Response of murine gamma delta T cells to the synthetic polypeptide poly-Glu50Tyr50.},
  author={Carol T. Cady and Michael Lahn and Marielle Vollmer and Moriya Tsuji and Sook Jae Seo and Claudia L. Reardon and Rebecca L O'brien and Willi K. Born},
  journal={Journal of immunology},
  year={2000},
  volume={165 4},
  pages={1790-8}
}
Random heterocopolymers of glutamic acid and tyrosine (pEY) evoke strong, genetically controlled immune responses in certain mouse strains. We found that pE50Y50 also stimulated polyclonal proliferation of normal gamma delta, but not alpha beta, T cells. Proliferation of gamma delta T cells did not require prior immunization with this Ag nor the presence of alpha beta T cells, but was enhanced by IL-2. The gamma delta T cell response proceeded in the absence of accessory cells, MHC class II… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…