Response of host inflammasomes to viral infection.

  title={Response of host inflammasomes to viral infection.},
  author={I-Yin Chen and Takeshi Ichinohe},
  journal={Trends in microbiology},
  volume={23 1},
Inflammasomes are multiprotein complexes that induce downstream immune responses to specific pathogens, environmental stimuli, and host cell damage. Components of specific viruses activate different inflammasomes; for example, the influenza A virus M2 protein and encephalomyocarditis virus (EMCV) 2B protein activate the nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome, whereas viral double-stranded RNA (dsRNA) activates… CONTINUE READING
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