Response of different mammary epithelial cell lines to a mammary derived growth inhibitor (MDGI).

@article{Lehmann1989ResponseOD,
  title={Response of different mammary epithelial cell lines to a mammary derived growth inhibitor (MDGI).},
  author={Werner M. Lehmann and Robert G. Widmaier and Peter W. de Langen},
  journal={Biomedica biochimica acta},
  year={1989},
  volume={48 1},
  pages={
          143-51
        }
}
MDGI, a 14.5-KDa protein, is a chemically defined growth inhibitor, which we have purified from lactating bovine mammary gland and characterized biologically in a mouse Ehrlich ascites mammary tumour (EAT) short term suspension culture. It has now been tested for its inhibitory activity on proliferation of four malignant mammary epithelial cell lines of human and mouse origin and normal human mammary epithelial cells. In all experiments, cells were brought to quiescence by serum or growth… CONTINUE READING

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