Response of body temperature and serum iron concentration to repeated pyrogen injection in rabbits

@article{Goelst1991ResponseOB,
  title={Response of body temperature and serum iron concentration to repeated pyrogen injection in rabbits},
  author={Kathleen Goelst and Helen P. Laburn},
  journal={Pfl{\"u}gers Archiv},
  year={1991},
  volume={417},
  pages={558-561}
}
We measured body temperature and serum iron concentration after five daily consecutive injections of febrile doses of Salmonella typhosa lipopolysaccharide (0.1 μg/kg) and two doses of Staphylococcus aureus cell walls (1×107 and 5×107 cells) in rabbits. Tolerance to endotoxin injection, as manifest by a significant attenuation in the body temperature elevation, developed after the first injection of endotoxin. The endotoxin-induced fall in serum iron concentration was attenuated significantly… CONTINUE READING

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References

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Showing 1-10 of 20 references

Mechanisms of fever. In: SchOnbaum E, Lomax P (eds) Thermoregulation pathology, pharmacology and therapy

  • R Hellon, Y Townsend, HP Laburn, D Mitchell
  • 1990
1 Excerpt

Vasopressin VI-receptors within the ventral septum of the rat brain are involved in endotoxin tolerance (ET)

  • M Wilkinson, N Kasting
  • Proc IUPS
  • 1989

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