Response of Hippocampal Synapses to Natural Stimulation Patterns

@article{Dobrunz1999ResponseOH,
  title={Response of Hippocampal Synapses to Natural Stimulation Patterns},
  author={Lynn E Dobrunz and Charles F. Stevens},
  journal={Neuron},
  year={1999},
  volume={22},
  pages={157-166}
}
We have studied the synaptic responses in hippocampal slices to stimulus patterns derived from in vivo recordings of place cell firing in a behaving rodent. We find that synaptic strength is strongly modulated during the presentation of these natural stimulus trains, varying 2-fold or more because of short-term plasticity. This modulation of synaptic strength is precise and deterministic, because the pattern of synaptic response amplitudes is nearly identical from one presentation of the train… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Place cell discharge is exintracellular recordings in rat neocortex

A. A. Fenton, R. U. Müller
  • Neuroscience
  • 1998
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

The neural code between neocortical pyramidal neurons depends on neurotransmitter release probability.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1997
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Temporal and spatial properfield [ see comments ]

J. Deuchars
  • Proc . Natl . Acad . Sci . USA
  • 1994
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The effect of temperature ated presynaptically and selffacilitation , mediated postsynaptically . on the sodium and potassium permeability changes in myelinated

L. Moore
  • J . Neurophysiol . J . Physiol .
  • 1963
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Hippocampal cellular activity: a brief history of space.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
VIEW 1 EXCERPT