Response of Cultured Macrophages to Mycobacterium Tuberculosis, with Observations on Fusion of Lysosomes with Phagosomes

@article{Armstrong1971ResponseOC,
  title={Response of Cultured Macrophages to Mycobacterium Tuberculosis, with Observations on Fusion of Lysosomes with Phagosomes},
  author={John A. Armstrong and Philip D. Hart},
  journal={The Journal of Experimental Medicine},
  year={1971},
  volume={134},
  pages={713 - 740}
}
The cytological response to the ingestion of tubercle bacilli by cultured mouse peritoneal macrophages has been studied by electron microscopy. Methods included a quantitative assessment based on systematic surveying of cell profiles, and of phagosomes and their contained bacteria, encountered in thin sections; classification of the sectioned bacteria into visibly damaged and apparently intact categories; prelabeling of dense granules (secondary lysosomes) with ferritin as an aid to identifying… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
268 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 268 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Morphology of mouse mononuclear phagocytes

  • J. G. Hirsch, M. E. Fedorko
  • In Mononuclear Phagocytes. R. Van Furth,
  • 1970

The fine structure of the mammalian lymphoreticular system

  • I. Cart
  • Int. Rev. Cytol
  • 1970

Electron microscopy of the vacuolar apparatus

  • Daems, W.Th, E. Wisse, P. Brederoo
  • 1969

Similar Papers

Loading similar papers…