Response in bone turnover markers during therapy predicts overall survival in patients with metastatic prostate cancer: analysis of three clinical trials

@inproceedings{Som2012ResponseIB,
  title={Response in bone turnover markers during therapy predicts overall survival in patients with metastatic prostate cancer: analysis of three clinical trials},
  author={Anirban Som and S Tu and Jun Liu and Xin Wang and Wei Qiao and Christopher J. Logothetis and Paul G. Corn},
  booktitle={British Journal of Cancer},
  year={2012}
}
Background:The bone-forming metastases of prostate cancer result from complex stromal–epithelial interactions within the tumour microenvironment. Autocrine–paracrine signalling pathways between prostate cancer epithelial cells, osteoblasts, and osteoclasts stimulate aberrant bone remodelling, and the activity of these three cell populations can be… CONTINUE READING