Response-guided treatment of cirrhotic chronic hepatitis B patients: multicenter prospective study.

Abstract

AIM To observe the effect of response-guided add-on therapy with adefovir (ADV) and lamivudine (LAM) in cirrhotic hepatitis B (CHB) patients. METHODS A total of 100 patients with CHB and cirrhosis were divided into three arms according to hepatitis B virus (HBV) DNA level after 24 wk LAM monotherapy: Arm A (complete response, HBV DNA ≤ 60 IU/mL, n = 49… (More)
DOI: 10.3748/wjg.v21.i2.653

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