Respiratory syncytial virus stimulation of vascular endothelial cell growth Factor/Vascular permeability factor.

  title={Respiratory syncytial virus stimulation of vascular endothelial cell growth Factor/Vascular permeability factor.},
  author={C G Lee and H J Yoon and Z. Zhu and Holger Link and Z. Wang and Jack M. Gwaltney and Marc Landry and Jack A. Elias},
  journal={American journal of respiratory cell and molecular biology},
  volume={23 5},
  • C. LeeH. Yoon J. Elias
  • Published 2000
  • Biology, Medicine
  • American journal of respiratory cell and molecular biology
We hypothesized that respiratory syncytial virus (RSV)-induced pathologies could be mediated, in part, by vascular active cytokines elaborated during virus infection. To address this hypothesis, we determined whether RSV stimulated vascular endothelial cell growth factor (VEGF)/vascular permeability factor (VPF) elaboration in vitro. Supernatants from unstimulated A549 cells and normal human bronchial epithelial cells contained modest levels of VEGF. In contrast, supernatants from RSV-infected… 

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