Respiratory syncytial virus infection is associated with an altered innate immunity and a heightened pro-inflammatory response in the lungs of preterm lambs

@inproceedings{Sow2011RespiratorySV,
  title={Respiratory syncytial virus infection is associated with an altered innate immunity and a heightened pro-inflammatory response in the lungs of preterm lambs},
  author={Fatoumata B. Sow and Jack M Gallup and Subramaniam Krishnan and Andriani C. Patera and JoAnn A Suzich and Mark R Ackermann},
  booktitle={Respiratory research},
  year={2011}
}
INTRODUCTION Factors explaining the greater susceptibility of preterm infants to severe lower respiratory infections with respiratory syncytial virus (RSV) remain poorly understood. Fetal/newborn lambs are increasingly appreciated as a model to study key elements of RSV infection in newborn infants due to similarities in lung alveolar development, immune response, and susceptibility to RSV. Previously, our laboratory demonstrated that preterm lambs had elevated viral antigen and developed more… CONTINUE READING