Respiratory syncytial virus induces the expression of 5-lipoxygenase and endothelin-1 in bronchial epithelial cells.

@article{Behera1998RespiratorySV,
  title={Respiratory syncytial virus induces the expression of 5-lipoxygenase and endothelin-1 in bronchial epithelial cells.},
  author={Aruna K. Behera and Mukesh Kumar and Hiroto Matsuse and Richard Funk Lockey and Shyam Sundar Mohapatra},
  journal={Biochemical and biophysical research communications},
  year={1998},
  volume={251 3},
  pages={704-9}
}
Respiratory syncytial virus (RSV) infection causes and exacerbates asthma, yet the mechanism by which RSV triggers asthma is poorly understood. Herein, an in vitro model of RSV infection was established using HEp-2 and BEAS-2B bronchial epithelial cell lines, and the expression of 5-lipoxygenase (5-LO), and endothelin-1 (ET-1) was examined. RSV infection… CONTINUE READING