Respiratory syncytial virus and recurrent wheeze in healthy preterm infants.

@article{Blanken2013RespiratorySV,
  title={Respiratory syncytial virus and recurrent wheeze in healthy preterm infants.},
  author={Maarten O Blanken and Maroeska Rovers and Jorine M Molenaar and Pauline L Winkler-Seinstra and Adam Meijer and Jan L. L. Kimpen and Louis J. Bont},
  journal={The New England journal of medicine},
  year={2013},
  volume={368 19},
  pages={
          1791-9
        }
}
BACKGROUND Respiratory syncytial virus (RSV) infection is associated with subsequent recurrent wheeze. Observational studies cannot determine whether RSV infection is the cause of recurrent wheeze or the first indication of preexistent pulmonary vulnerability in preterm infants. The monoclonal antibody palivizumab has shown efficacy in preventing severe RSV infection in high-risk infants. METHODS In the double-blind, placebo-controlled MAKI trial, we randomly assigned 429 otherwise healthy… CONTINUE READING
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