Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone.

  title={Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone.},
  author={Lawrence J Folinsbee and Donald H. Horstman and H R Kehrl and S. Harder and S Abdul-Salaam and P J Ives},
  journal={American journal of respiratory and critical care medicine},
  volume={149 1},
Repeated exposure to high concentrations of ozone results first in augmentation (typically on the second day) and then attenuation of pulmonary response in humans. To determine the effects of repeated prolonged low-concentration ozone exposure, we exposed 17 healthy nonsmoking male subjects to 0.12 ppm ozone for 6.6 h on 5 consecutive days. Subjects were also exposed once to filtered air. Volunteers exercised at a ventilation of approximately 39 L/min for 50 min of each hour during the exposure… CONTINUE READING


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