Respiratory protein–generated reactive oxygen species as an antimicrobial strategy

  title={Respiratory protein–generated reactive oxygen species as an antimicrobial strategy},
  author={Naxin Jiang and Nguan Soon Tan and Bow Ho and Jeak Ling Ding},
  journal={Nature Immunology},
The evolution of the host-pathogen relationship comprises a series of invasive-defensive tactics elicited by both participants. The stereotype is that the antimicrobial immune response requires multistep processes. Little is known about the primordial immunosurveillance system, which probably has components that directly link sensors and effectors. Here we found that the respiratory proteins of both the horseshoe crab and human were directly activated by microbial proteases and were enhanced by… CONTINUE READING
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Spatial and temporal coordination of expression of immune response genes during Pseudomonas aeruginosa infection of horseshoe crab, Carcinoscorpius rotundicauda

  • Ding, J.L
  • Genes Immun
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