Respiratory muscle activity and oxygenation during sleep in patients with muscle weakness.

@article{White1995RespiratoryMA,
  title={Respiratory muscle activity and oxygenation during sleep in patients with muscle weakness.},
  author={Jerry White and Michael J. Drinnan and Andrew Smithson and Clive J. Griffiths and Grant Gibson},
  journal={The European respiratory journal},
  year={1995},
  volume={8 5},
  pages={807-14}
}
Patients with respiratory muscle weakness show nocturnal hypoventilation, with oxygen desaturation particularly during rapid eye movement (REM) sleep, but evidence in individuals with isolated bilateral diaphragmatic paresis (BDP) is conflicting. The effect of sleep on relative activity of the different respiratory muscles of such patients and, consequently, the precise mechanisms causing desaturation have not been clarified. We have studied eight patients, four with generalized muscle weakness… CONTINUE READING
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