Respiratory mucous secretions in patients with cystic fibrosis: relationship between levels of highly sulfated mucin component and severity of the disease.

@article{Chace1983RespiratoryMS,
  title={Respiratory mucous secretions in patients with cystic fibrosis: relationship between levels of highly sulfated mucin component and severity of the disease.},
  author={Kenneth V. Chace and D S Leahy and Richard Tyler Martin and Raoul Carubelli and Marinus Flux and Goverdhan P. Sachdev},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1983},
  volume={132 2},
  pages={
          143-55
        }
}
The tracheobronchial secretions from cystic fibrosis patients contained higher levels of protein, DNA and sialic acid than the tracheobronchial secretions from healthy donors. In contrast, the neutral hexose content in CF secretions was strikingly lower than in secretions from normal subjects. The levels of neutral hexose and sialic acid in the CF secretions were found to increase with increasing severity of the disease. The alterations in the levels of these chemical parameters in the… CONTINUE READING
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