Respiratory distress with pamidronate treatment in infants with severe osteogenesis imperfecta.

@article{Munns2004RespiratoryDW,
  title={Respiratory distress with pamidronate treatment in infants with severe osteogenesis imperfecta.},
  author={Craig F J Munns and Frank Rauch and Richard J. Mier and Francis H Glorieux},
  journal={Bone},
  year={2004},
  volume={35 1},
  pages={231-4}
}
This report aims to describe the adverse respiratory events associated with the first pamidronate cycle in four infants with severe osteogenesis imperfecta (OI) who were less than 2 years of age. Fifty-nine infants with severe OI were commenced on cyclical intravenous pamidronate therapy in an observation trial. Routine observations were measured during each infusion cycle. During the first treatment cycle, four infants (7%) with preexisting respiratory compromise developed respiratory distress… CONTINUE READING
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Connective Tissue and Its Heritable Disorders

  • P Byers, B Steinmann, editors
  • 2002
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