Respiratory control in neonatal rats exposed to prenatal cigarette smoke.

@article{Pendlebury2008RespiratoryCI,
  title={Respiratory control in neonatal rats exposed to prenatal cigarette smoke.},
  author={Jonathan D Pendlebury and Richard J. A. Wilson and Shehr Bano and Kathleen J Lumb and Jennifer M Schneider and Shabih U Hasan},
  journal={American journal of respiratory and critical care medicine},
  year={2008},
  volume={177 11},
  pages={1255-61}
}
RATIONALE Prenatal cigarette smoke (CS) exposure, increased environmental temperature, and hypoxic episodes have been postulated as major risk factors for sudden infant death syndrome. OBJECTIVES To test the hypothesis that maternal CS exposure disrupts eupneic breathing and depresses breathing responses of neonatal rats to thermal and hypoxic challenges. METHODS Experiments were performed on 1-week-old rat pups exposed prenatally to CS (n = 39) or room air (sham; n = 30). Breathing… CONTINUE READING