Respiratory control during exercise in patients with cardiovascular disease.

  title={Respiratory control during exercise in patients with cardiovascular disease.},
  author={Akira Koike and Michiaki Hiroe and Koichi Taniguchi and Fumiaki Marumo},
  journal={The American review of respiratory disease},
  volume={147 2},
The pathophysiologic mechanism for exertional dyspnea, the main symptom of patients with heart failure, has not been fully clarified. To determine the relationship between exercise hyperpnea and the lactic acidosis in patients with heart failure, we evaluated ventilation during incremental exercise both below and above the lactic acidosis threshold in 16 normal subjects and in 48 patients with cardiovascular disease while expired gas was analyzed continuously. The peak oxygen uptake and oxygen… CONTINUE READING


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