Respiratory control and sternohyoid muscle structure and function in aged male rats: Decreased susceptibility to chronic intermittent hypoxia

@article{Skelly2012RespiratoryCA,
  title={Respiratory control and sternohyoid muscle structure and function in aged male rats: Decreased susceptibility to chronic intermittent hypoxia},
  author={J. Skelly and D. Edge and Christine M. Shortt and J. Jones and K. O'Halloran},
  journal={Respiratory Physiology & Neurobiology},
  year={2012},
  volume={180},
  pages={175-182}
}
  • J. Skelly, D. Edge, +2 authors K. O'Halloran
  • Published 2012
  • Medicine
  • Respiratory Physiology & Neurobiology
  • Obstructive sleep apnoea syndrome (OSAS) is a common respiratory disorder characterized by chronic intermittent hypoxia (CIH). We have shown that CIH causes upper airway muscle dysfunction in the rat due to oxidative stress. Ageing is an independent risk factor for the development of OSAS perhaps due to respiratory muscle remodelling and increased susceptibility to hypoxia. We sought to examine the effects of CIH on breathing and pharyngeal dilator muscle structure and function in aged rats… CONTINUE READING
    Sex differences in murine sternohyoid muscle tolerance of acute severe hypoxic stress.
    3

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