Respiratory burst of intestinal macrophages in inflammatory bowel disease is mainly caused by CD14+L1+ monocyte derived cells.

@article{Rugtveit1995RespiratoryBO,
  title={Respiratory burst of intestinal macrophages in inflammatory bowel disease is mainly caused by CD14+L1+ monocyte derived cells.},
  author={Jarle Rugtveit and Guttorm Haraldsen and Anne Kirsti M H\og{\aa}sen and Arne Olav Bakka and P E R Brandtzaeg and Helge Scott},
  journal={Gut},
  year={1995},
  volume={37 3},
  pages={367-73}
}
Macrophages play a crucial role in intestinal mucosal defence, forming dense subepithelial aggregates, particularly in the colon. One of their important bactericidal mechanisms is production of oxygen radicals but this may damage the intestinal epithelium, perhaps as an early step in inflammatory bowel disease (IBD). The potential for release of oxygen radicals from mucosal macrophages in IBD was measured and whether a difference exists between newly arrived (CD14+L1+) monocyte-like cells and… CONTINUE READING
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