Respiratory and cerebrovascular responses to hypoxia and hypercapnia in familial dysautonomia.

@article{Bernardi2003RespiratoryAC,
  title={Respiratory and cerebrovascular responses to hypoxia and hypercapnia in familial dysautonomia.},
  author={Luciano Bernardi and Max J Hilz and Brigitte Stemper and Claudio Passino and Goetz C Welsch and Felicia B. Axelrod},
  journal={American journal of respiratory and critical care medicine},
  year={2003},
  volume={167 2},
  pages={141-9}
}
Although cardiorespiratory complications contribute to the high morbidity/mortality of familial dysautonomia (FD), the mechanisms remain unclear. We evaluated respiratory, cardiovascular, and cerebrovascular control by monitoring ventilation, end-tidal carbon dioxide (CO2-et), oxygen saturation, RR interval, blood pressure (BP), and midcerebral artery flow velocity (MCFV) during progressive isocapnic hypoxia, progressive hyperoxic hypercapnia, and during recovery from moderate hyperventilation… CONTINUE READING

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