Respiratory and cardiovascular effects of WP-934 in guinea pigs.

  title={Respiratory and cardiovascular effects of WP-934 in guinea pigs.},
  author={Tadatoshi Hashimoto and Yoshihiro Toyoda and Toru Taniguchi and Yoshiaki Kitazawa},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  volume={17 1},
WP-934 is a newly developed reversible thermo-setting in situ gelling ophthalmic solution containing timolol. We investigated the effects of WP-934 on the respiratory and cardiovascular systems in guinea pigs and compared them with those of the conventional ophthalmic solution of timolol. At 30 min after instillation of timolol 0.5%, the airway… CONTINUE READING