Respiratory Mechanics and Intrinsic PEEP during Ketamine and Halothane Anesthesia in Young Children

@article{Shulman1988RespiratoryMA,
  title={Respiratory Mechanics and Intrinsic PEEP during Ketamine and Halothane Anesthesia in Young Children},
  author={David L. Shulman and Ephraim Bar-Yishay and Simon Godfrey},
  journal={Anesthesia \& Analgesia},
  year={1988},
  volume={67},
  pages={656–662}
}
Static compliance of the respiratory system (Crs) was measured by the interrupter technique in 18 anesthetized children to compare the effects of ketamine on Crs with those of halothane. Crs was the slope of the pressure-volume (P-V) curve obtained by repeated brief airway occlusions throughout relaxed expiration, and the intercept of the P-V curve on the pressure axis was the intrinsic positive end-expiratory airway pressure (PEEPi). Expiratory time (Te) was measured during a period of quiet… Expand
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References

SHOWING 1-10 OF 18 REFERENCES
Determinants of end expiratory volume in young children during ketamine or halothane anesthesia.
TLDR
It is concluded that, in children during ketamine anesthesia, tau is prolonged and, in these children, the relationship of Te to t Tau is an important determinant of FRC-Vrs. Expand
Interrupter technique for measurement of respiratory mechanics in anesthetized humans.
TLDR
The interrupter technique allows for simultaneous determination of the passive elastic as well as flow-resistive properties of the total respiratory system and may be employed as a useful and simple criterion to confirm the presence of respiratory muscle relaxation. Expand
Passive respiratory mechanics in newborns and children.
TLDR
The passive expiratory flow-volume technique is simple, noninvasive, and appears to provide accurate measurements of respiratory mechanics in the newborn and in paralyzed children. Expand
Interrupter technique for measurement of respiratory mechanics in anesthetized cats.
TLDR
In six spontaneously breathing anesthetized cats, airflow, changes in lung volume, and tracheal and esophageal pressures were measured, and respiratory system elastance and flow resistance were determined. Expand
Hypoxemia after General Anesthesia in Children
TLDR
There was no statistical difference in SaO2 between patients who received inhalation anesthesia alone and those who were given narcotics, and there was also no correlation between postoperative reduction inSaO2 and duration of anesthesia or patient age. Expand
The Effect of Ketamine on the Functional Residual Capacity in Young Children
TLDR
It is concluded that ketamine does not affect resting lung volume in young children and anesthetized children following elective surgery. Expand
Measurement of static compliance of the total respiratory system in patients with acute respiratory failure during mechanical ventilation. The effect of intrinsic positive end-expiratory pressure.
In mechanically ventilated patients with acute respiratory failure, the static compliance of the total respiratory system is conventionally obtained by dividing the tidal volume by the differenceExpand
Effects of Ketamine and Halothane on Increased Respiratory Resistance Provoked by Ultrasonic Aerosols
TLDR
It is concluded that halothane remains a useful drug for patients who have increased respiratory resistance and any utility of ketamine in anesthetic management of asthmatie patients must be on a basis other than a bron-chodilator side-effect. Expand
The Mechanical Properties of the Respiratory System during Anesthesia
  • H. Don
  • Medicine
  • International anesthesiology clinics
  • 1977
TLDR
The changes in lung compliance, FRC, and A-aDo2 appear to have similar characteristics, and they are not influenced by depth or type of general anesthesia or the presence of neuromuscular blockade. Expand
Comparison of esophageal, tracheal, and mouth occlusion pressure in patients with chronic obstructive pulmonary disease during acute respiratory failure.
TLDR
Because in patients with COPD with upper airways bypassed (tracheostomized or intubated) the changes in esophageal and tracheal pressure during occluded respiratory efforts were similar, it is concluded that the difference between esophagal and mouth occlusion pressure is due to the tissue compliance of the oropharynx. Expand
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